DUOPIL 2/500mg Tablet 10’S

Product Highlights

• Dual-action oral therapy for type 2 diabetes

• Improves insulin response and lowers liver glucose production

• Suitable when monotherapy is insufficient

• Cost-effective fixed-dose combination

• Helps minimize diabetes-related long-term complications

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Product Introduction

DUOPIL 2/500mg Tablet is indicated in adults for the management of type 2 diabetes when diet, exercise, and a single antidiabetic agent do not provide sufficient control. It is not recommended for use in type 1 diabetes or diabetic ketoacidosis. Along with this medication, maintaining a healthy lifestyle, meal planning, and regular physical activity are crucial.

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Key Benefits

• Effective Blood Sugar Control: Acts through two different mechanisms to regulate blood glucose

• Reduces Risk of Hypoglycemia: Balanced action compared to high-dose monotherapies

• Supports Weight Neutrality: Metformin helps in weight management

• Convenient Combination Therapy: Reduces the number of pills needed daily

• Protects Against Diabetes Complications: Helps prevent nerve damage, kidney issues, and heart disease

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How It Works

DUOPIL 2/500mg Tablet contains:

• Glimepiride: A sulfonylurea that stimulates insulin secretion from the pancreas

• Metformin: A biguanide that reduces glucose production by the liver, delays intestinal glucose absorption, and improves insulin sensitivity
  Together, they enhance glucose uptake and utilization, effectively lowering both fasting and post-meal blood glucose levels.

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Usage Instructions

• Take DUOPIL 2/500mg Tablet as advised by your physician

• Swallow the tablet whole with water, preferably with meals

• Do not chew or crush the tablet

• Take at the same time each day for best results

• Do not stop the medication without consulting your doctor

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Side Effects

Common Side Effects:

• Taste disturbances

• Diarrhea

• Abdominal pain

• Loss of appetite

Serious Side Effects (Seek Immediate Help):

• Lactic Acidosis (nausea, muscle pain, tiredness, difficulty breathing)

• Severe Hypoglycemia (shaking, confusion, paleness, sweating)

• Allergic Reactions (rash, swelling, shortness of breath)

• Liver Inflammation (yellowing of eyes/skin)

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Safety Information

• Pregnancy: ❌ Not recommended; consult a doctor

• Breastfeeding: ❌ Avoid use during breastfeeding

• Driving: ⚠️ May impair alertness if sugar levels fluctuate

• Alcohol: ⚠️ Avoid, as it increases the risk of hypoglycemia and lactic acidosis

• Kidney: ⚠️ Not suitable for severe kidney disease; monitor function if used

• Liver: ⚠️ Not recommended in severe liver conditions

• Heart Disease: ❌ Contraindicated in acute heart failure or recent heart attack

• Children: ❌ Not for those under 18 years

• Elderly: ⚠️ Use with caution, especially if kidney function is compromised

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Good to Know

• Not recommended for type 1 diabetes or diabetic ketoacidosis

• Avoid long gaps between meals to prevent low blood sugar

• Do not consume alcohol during treatment

• Monitor blood sugar levels regularly

• Keep glucose or sweets handy for emergencies

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Quick Tips

• Take with food to avoid gastric discomfort

• Stick to a consistent schedule for medication and meals

• Stay active and follow your diabetic diet plan

• Carry ID stating that you are diabetic

• Inform your doctor about all other ongoing medications

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FAQs

Q: What is DUOPIL 2/500mg Tablet used for?
A: It is used in adults to manage type 2 diabetes when blood sugar is not adequately controlled by diet, exercise, or a single antidiabetic medication.

Q: How does DUOPIL 2/500mg Tablet work?
A: Glimepiride increases insulin secretion from the pancreas, while Metformin reduces glucose production in the liver and increases insulin sensitivity. Together, they improve overall blood sugar control.

Q: Can DUOPIL 2/500mg Tablet be taken during pregnancy?
A: No, it is not recommended during pregnancy. Speak to your doctor about safer alternatives like insulin.

Q: When should I take DUOPIL 2/500mg Tablet?
A: It is usually taken with meals to minimize side effects like nausea. Follow your doctor’s advice for best results.

Q: Is DUOPIL 2/500mg Tablet safe for elderly patients?
A: It should be used with caution, especially in patients aged 65 and above, and is not recommended for those over 75 with impaired kidney function. Regular monitoring is necessary.