DUOPIL 1/500mg Tablet 10’S

Product Highlights

• Dual-action control of blood glucose

• Helps reduce fasting and post-meal sugar levels

• Suitable for adults with uncontrolled type 2 diabetes

• May be used when single-drug therapy fails

• Economical option with reliable efficacy

---

Product Introduction

DUOPIL 1/500mg Tablet is indicated for the treatment of type 2 diabetes in adults who have not achieved sufficient blood sugar control with diet, exercise, and either Glimepiride or Metformin alone. It should be taken along with proper dietary habits and regular physical activity as prescribed by the physician.

---

Key Benefits

• Enhanced Glycemic Control: Combines insulin secretion stimulation and insulin sensitivity improvement

• Reduces Liver Glucose Output: Lowers hepatic glucose production

• Improves Insulin Response: Enhances body’s use of insulin

• Convenient Dosing: Combines two agents in one tablet for ease

• Minimizes Long-Term Complications: Helps prevent damage to eyes, kidneys, and nerves

---

How It Works

DUOPIL 1/500mg Tablet contains:

• Glimepiride, a sulfonylurea that stimulates insulin secretion from the pancreas

• Metformin, a biguanide that decreases glucose production in the liver, delays glucose absorption from the intestines, and improves the body’s insulin sensitivity
  Together, they lower blood glucose levels and help maintain steady glycemic control.

---

Usage Instructions

• Take DUOPIL 1/500mg Tablet exactly as prescribed by your doctor

• Swallow the tablet whole with water, preferably with meals

• Do not crush or chew the tablet

• Stick to a consistent daily routine and monitor your blood sugar regularly

• Do not skip doses or stop treatment without consulting your doctor

---

Side Effects

Common:

• Taste disturbance

• Diarrhea

• Abdominal pain

• Loss of appetite

Seek immediate medical attention if you notice:

• Signs of lactic acidosis (e.g., abdominal pain, vomiting, muscle cramps, fatigue)

• Severe hypoglycemia (e.g., sweating, confusion, shakiness, fainting)

• Allergic reactions (e.g., rash, hives, breathing difficulty, swelling)

• Signs of liver inflammation (e.g., yellowing of the eyes/skin, dark urine)

---

Safety Information

• Pregnancy: ❌ Not recommended; consult your doctor for safer alternatives

• Breastfeeding: ❌ Contraindicated, as the drug may pass into breast milk

• Driving: ⚠️ Use caution—risk of hypoglycemia may affect alertness

• Alcohol: ⚠️ Avoid; increases the risk of lactic acidosis and hypoglycemia

• Kidney Impairment: ⚠️ Not recommended in severe cases; use with caution under medical supervision

• Liver Disease: ⚠️ Not recommended in severe liver dysfunction

• Heart Disease: ❌ Contraindicated in acute heart failure or recent heart attack

• Children: ❌ Not for use in individuals under 18 years

• Elderly: ⚠️ Use with caution, especially in those over 75 years with impaired kidney function

---

Good to Know

• Not suitable for type 1 diabetes or diabetic ketoacidosis

• Regular kidney and liver function monitoring may be needed

• Take during meals to reduce GI side effects

• Do not take this medication if fasting or consuming less food than usual

• Follow a consistent meal schedule to reduce risk of hypoglycemia

---

Quick Tips

• Take with meals to minimize stomach upset

• Do not skip meals—maintain regular eating habits

• Monitor blood glucose levels regularly as advised

• Avoid alcohol during treatment

• Keep sugar or glucose handy to treat mild hypoglycemia

• Inform your doctor about all ongoing medications

---

FAQs

Q: What is DUOPIL 1/500mg Tablet used for?
A: It is used for managing type 2 diabetes in adults when diet, exercise, and single-drug therapy don’t provide adequate blood sugar control.

Q: Can I take DUOPIL 1/500mg Tablet during pregnancy?
A: No, it is not recommended during pregnancy. Consult your doctor for alternative diabetes management options like insulin.

Q: How does DUOPIL 1/500mg Tablet work?
A: It contains Glimepiride, which stimulates insulin release, and Metformin, which lowers sugar production in the liver and improves insulin sensitivity.

Q: Can I drink alcohol while on DUOPIL 1/500mg Tablet?
A: No. Alcohol increases the risk of lactic acidosis and hypoglycemia. Avoid it during treatment.

Q: How should I take DUOPIL 1/500mg Tablet?
A: Take it as advised by your doctor, preferably with meals. Do not skip doses or stop without consulting your physician.

Q: Is it safe for elderly patients?
A: It should be used cautiously in patients aged 65 and above, especially if they have kidney problems. Your doctor may monitor kidney function regularly.